The exploration of network motifs as potential drug targets from post-translational regulatory networks
نویسندگان
چکیده
منابع مشابه
The exploration of network motifs as potential drug targets from post-translational regulatory networks
Phosphorylation and proteolysis are among the most common post-translational modifications (PTMs), and play critical roles in various biological processes. More recent discoveries imply that the crosstalks between these two PTMs are involved in many diseases. In this work, we construct a post-translational regulatory network (PTRN) consists of phosphorylation and proteolysis processes, which en...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2016
ISSN: 2045-2322
DOI: 10.1038/srep20558